Optimization of Pellets Containing Solid Dispersion Prepared by Extrusion/Spheronization Using Central Composite Design and Desirability Function
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چکیده
منابع مشابه
Optimization of Pellets Containing Solid Dispersion Prepared by Extrusion/Spheronization Using Central Composite Design and Desirability Function
Furosemide is a class IV biopharmaceutical classification system drug having poor water solubility and low bioavailability due to the hepatic first-pass metabolism and has a short half-life of 2 h. To overcome the above drawback, this study was carried to prepare and evaluate the pellets containing furosemide solid dispersion (SD) for oral administration prepared by extrusion/spheronization. SD...
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ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2012
ISSN: 0975-1483
DOI: 10.4103/0975-1483.100020